This guidance document addresses the approach to be taken for providing information on potential toxic effects, indicate target organs of toxicity and the possibility of accumulation, and to provide an estimate of a no-observed-effect level (NOAEL) of feed ingredients.

Suggested citation: ICCF EWG ‘Sub-chronic oral toxicity testing in laboratory animals’. Johnson D.¹, Muir B.², Ponghellini M.³, Matulka R.⁴, Thiel A.⁵, Campbell L.⁶, Eapen A.⁷, 2019. Guidance on the sub-chronic testing in laboratory animals. ICCF 2019. 31 pages

1 CFIA / 2 FDA / 3 EFSA / 4 AFIA / 5 FEFANA / 6 ANAC / 7 IFIF